Portfolio

Selected Portfolio Companies

BioPharma - Alzheimer's Disease and Brain Health Therapeutics

Athira Pharma is a therapeutics company that has a novel platform of disease-modifying regenerative small molecules, particularly relevant to neurodegenerative diseases with a focus on Alzheimer’s.
AZTherapies is a biopharmaceutical company with a novel combination drug regimen to address the neuroinflammatory component of Alzheimer's disease.
Cognition Therapeutics is a biopharmaceutical company developing small-molecule therapeutics that address the toxic oligomeric proteins that cause membrane trafficking dysfunction, triggering neurodegenerative diseases such as Alzheimer’s disease
MedaRed therapeutics target fibrin for inflammation and neurological diseases
NeuroTherapia NeuroTherapia is developing new chemical entities targeting CB2 receptors on microglia, significantly reducing the expression of inflammatory agents resulting in neuronal survival and proliferation.
PharmatrophiX is a biopharmaceutical company focused on the development of disease-modifying small molecule drugs, targeting the mechanisms underlying neurodegenerative disorders.
Tetra Therapeutics is a clinical stage company developing a platform of pharmaceutical therapies targeting Type 4 phosphodiesterases (PDE4) enzymes in multiple neurological conditions including Fragile X Syndrome, Alzheimer’s Disease, Traumatic Brain Injury (TBI), Multiple Sclerosis (MS), and Chronic Traumatic Encephalopathy (CTE).
Tiaki Therapeutics has developed a proprietary in vitro microglia platform for the discovery of new microglial functions in dementias and has found a way to regulate and restore homeostatic function for the treatment of dementia.
Yumanity Therapeutics is taking a new approach to neurodegenerative disease drug discovery and development by correcting the cellular pathologies driven by misfolded proteins, the altered biology or phenotypes.

Prior Investments

Cortexyme is developing novel treatments for altering the course of Alzheimer's and other neurological diseases. The platform is based on a new theory of the cause of Alzheimer's, targeting a specific, undisclosed pathogen tied to neurodegeneration. Cortexyme is publicly traded since 2019 (NASDAQ: CRTX). Co-investors included Pfizer Ventures, Takeda Ventures, Sequoia Capital, Breakout Labs, Breakout Ventures, Verily Life Sciences, EPIQ Capital Group, the Lamond Family and Vulcan Capital.

BioTech - Technology Platforms as Tools to Accelerate Biomedical Research, Drug Development, and Clinical Trials

Aether repurposes enzymes to create new compounds and manufacturing process by utilizing a high-throughput robotic laboratory
Alzeca Biosciences develops novel, targeted Magnetic Resonance (MR) imaging agents for the early detection and diagnosis of Alzheimer’s Disease and other neurodegenerative diseases. An MRI based approach has a significantly lower cost, is widely available around the world, and has no radiation.
Atomwise neural network technology, called AtomNet, evaluates digital libraries of chemical compounds in search of novel small molecules to improve screening and accelerate the drug discovery process.
Cogstate computerized cognitive assessment technology delivers highly sensitive measures of cognition for clinical trials, healthcare diagnostics, academic research and brain injury. These validated cognitive tests are the center of Cogstate solutions for recruiting and screening clinical trial participants (Precision Recruitment™), measuring drug safety and efficacy endpoints (Cogstate Clinical Trials™), and tools to detect cognitive change in patients (COGNIGRAM®). Cogstate Rater Services provide expert rater training and monitoring support to minimize human error in traditional paper-and-pencil cognitive tests in clinical trials.
Cytovale is a medical device company that has developed an innovative approach for early detection of sepsis.
Echo Laboratories Revolve is a tablet-driven bright field and fluorescent hybrid microscope supporting both upright and inverted formats with proprietary cloud-connected software to improve imaging, analysis, and collaboration.
Envisagenics applies computational biology with RNA-sequencing to accelerate pharmaceutical candidate selection and biomarker development
GenomSys utilizes an ISO-compliant format, MPEG-G, to standardize genomic data, enabling interoperability and efficient processing of genetic information.
Hyperfine Research is developing devices and software to improve healthcare. The company is currently operating in stealth.
Paradromics neural interface technologies will deliver high-volume, bidirectional data streaming capabilities between brains and computers, initially targeting applications to assist physically disabled patients.
Strateos automates chemistry and biology processes, coupled with tissue analysis, in a closed-loop robotic laboratory to accelerate science and drug discovery. The company was formed in June 2019 as a result of a merger between 3Scan and Transcriptic.
System1 Biosciences is a neurotherapeutics platform company that is developing organoid disease models to discover novel drugs for neurological disorders.
Vium empowers biomedical investigators with technology that accelerates the preclinical drug discovery and development pipeline. Researchers can design, run, and analyze experiments that rapidly surface insights and high volumes of quality data while improving the speed and reproducibility of preclinical research.
Zebra Medical Vision applies computer vision and machine learning to medical imaging records in order to understand the risk profile of patients, detect and predict disease and assist in building and managing preventative care programs.

Prior Investments

Basis Science developed the world’s most advanced wearable health tracker. The company was acquired by Intel in 2014. Co-investors included Mayfield Fund, Norwest Venture Partners, DCM, Intel Capital.
goBalto develops next-generation solutions that simplify and accelerate clinical study startup in the pharmaceutical, biotechnology, and medical device industries. With a proven commitment to customer success, disruption, and optimization, GoBalto is changing the way global pharma and CRO approach business processes. The company was acquired by Oracle in 2018. Co-investors included Aberdare Ventures, Qualcomm, EDBI and Mitsui.

IT Software, Infrastructure, and Security

AuthenticVision develops technologies for brand protection and real-time marketing with mobile applications for the identification of counterfeit goods. The core technology was developed at the University of Applied Science, Salzburg, Austria.
Keyssa is the next generation wireless connector, capable of 6 Gigabits per second delivered across a secure, protocol agnostic EHF transmission.
NativeWaves allows viewers to select multiple perspectives for live events via mobile device.
Virtual Power Systems (VPS) provisions Software-Defined Power to Data Centers via intelligent and automated power provisioning to server farms. VPS technology increases reliability, reduces power losses and simplifies the power infrastructure across the industry.
Wickr is a communications platform backed by multi-layer encryption that provides private and untraceable transmission, delivery, and storage across any medium (email, messaging, video, and social media.) The technology can be overlaid on existing network platforms and has the potential to become the go-to application for safe and secure communication amongst corporate/government enterprises, gaming, and personal accounts.

Prior Investments

Podium Data enables businesses to rapidly consolidate all their data into manageable Hadoop-based data lakes for faster, more effective analytics and insights. The company was acquired by Qlik in 2018.
SST ShotSpotter Technology is a gunfire detection system of acoustic sensors and analytics to precisely locate gunfire across urban and rural environments for law enforcement, homeland security, private security, and military markets. ShotSpotter is publicly traded since 2017 (NASDAQ: SSTI). Co-investors included Lauder Partners, Levensohn Venture Partners, Claremont Creek, City Light, and Labrador Ventures.

Connected Devices

Atmosic wireless technology improves radio performance and battery life for IoT and connected device applications.
Eargo is an audio hardware company revolutionizing the hearing experience.
Jawbone Health helps detect lifestyle diseases and manage existing conditions to affect health outcomes
Motiv Ring performs high performance health monitoring and analytics for exercise, sleep, and daily living.
Noon Home lighting controls deliver intelligent automation and enable creative scenes and layered lighting for residential and commercial lighting.

Prior Investments

August builds products that make life simpler, allowing physical environments to seamlessly respond to user behavior. The August Smart Lock, the company’s flagship product, provides secure access to the home by controlling who can and cannot enter, without the need for keys or codes, managed through your smartphone. The company was acquired by Assa Abloy in 2017. Co-investors included Maveron, Bessemer Venture Partners, Comcast Ventures and Qualcomm Ventures.

3D Printing

Mixed Dimensions printing technology enables the market for high quality 3d printable objects. The MXD3D cloud based tool heals 3D models, and enables frame-accurate 3D printable content creation derived from gaming and other media.

Prior Investments

New Matter was founded in 2014 with a mission to bring 3D printing to every home, school, and office through its flagship product, the MOD-t. Slated for release in late 2015, the MOD-t will be one of the most affordable 3D printers on the market and will be integrated with New Matter’s online store of 3D printable designs, allowing users of all skill levels to find, customize, and print great objects.

Aerospace

Icon Aircraft is redefining the small aircraft experience for pilots of all age and experience levels with the Icon A5 amphibious light sport aircraft.
Phase Four plasma propulsion systems improve navigation and efficiency for in-orbit satellite missions
Stellar Labs aviation marketplace provides a new experience for procuring private aircraft charter with real-time price quotes while helping operators optimize their fleet.
Ursa Major Technologies manufactures propulsion systems for micro- and nano-satellite launch vehicles.

Virtual Reality and Augmented Reality

8i is transforming video capture and playback to deliver a new medium for all display devices.
DigiLens holographic optical waveguide technology and material science delivers unique optical solutions for display and imaging applications. Digilens is a leader in Switchable Bragg Grating (SBG) technologies.
Lightform creates simple, powerful tools that connect the real and digital worlds through computer vision and projected augmented reality.
Mojo Vision is currently operating in stealth.
Niantic Labs is a mobile software company focused on location-based augmented reality games. The company’s first title, Pokémon Go, launched in July 2016.
Ultrahaptics uses ultrasound waves to build touchless and gesture-based user interfaces that provide tactile sensations with mid-air virtual objects

Prior Investments

AltSpaceVR is a virtual reality software company bringing two-dimensional web content into shared virtual spaces and extending the web to create fully holographic experiences. The company was acquired by Microsoft in 2017. Co-investors included Tencent, GV, Formation 8 and Comcast Ventures.
Chirp Microsystem ultrasonic transceivers generate real-time 3D depth mapping for AR/VR, drones, and Connected Devices. The company was acquired by TDK in 2018.
Eyefluence embedded systems translate intent into action through human eye-driven UI/UX technologies for head mounted displays (HMDs). The company was acquired by Google in 2016. Co-investors include Jazz Ventures Partners, Intel Capital and Motorola Solutions Venture Capital.

Materials Science and Manufacturing Sustainability

Kuprion nanocopper pastes and inks provide higher performance alternatives to lead free solder, AuSn, and NanoSilver for electronic components and assemblies.
Opus 12 applies electrochemical processes to recycled industrial waste products, starting with CO₂ , to efficiently produce useful chemicals and fuels.
Phylagen technology identifies supply chain sources using the environmental microbiome.
Plethora technology provides on-demand CNC machining design analysis, estimating, and fulfillment of high-quality custom prototypes and end-production parts.
Tempo Automation’s connected factory is the world's fastest printed circuit board assembly (PCBA) manufacturing service, powered by proprietary automation software, creating an unbroken digital thread from design to delivery for rapid prototyping, high-volume design optimization, as well as low-volume high-precision runs.